Cannabidiol - CBD: How it Benefits Our Bodies

The cannabis plant has three species, ruderalis, indica and sativa. CBD comes from Hemp, a subspecies of sativa. Cannabinoids have been used throughout history(some records even indicate over 3000 years of use). Even our former presidents James Madison and George Washington used to maintain a crop of Hemp while separating the female plants(known for their higher THC content) for a ‘private stock’. Why was the use so popular, especially for the non-psychotropic CBD?

CBD promotes a feeling of relaxation by attaching to nerve receptors throughout the body. These nerve receptors release serotonin and help to release chemicals responsible for the ‘Runner’s High’ sensation; anandamide and 2-AG. What this means is that CBD helps to mimic post workout responses in the body, such as checking for damage and repairing. Research shows that CBD works best within a ‘Goldilocks’ zone, meaning, finding the specific dosage is paramount to achieving effects from CBD. Higher is not necessarily better as the exact dosage for an individual might be a low amount. So, when trying CBD, always start with a low dose, even in the 5-15mg range, to start.

Another consideration is how the CBD is carried. Is it an oral or topical? Oral application tends to last longer and touches on deeper nerve receptors throughout the organs. The digestive system does act on CBD, reducing the effectiveness for surface issues, but focusing them on the organs, especially liver. This can help with IBS, Crohn's, and even insulin resistance. A topical application does diffuse into Nerve receptors at the skin and usually at a rate relative to the amount(higher amount=faster absorption). Skin absorption is better in areas of denser hair follicles, and many follicles are usually located where the neck meets the skull; This is also directly over some of the most important nerves in your body. Topicals are great for more surface conditions such as arthritis, some inflammation, and skin conditions.

CBD can also be inhaled. When inhaled, the digestive system and skin play no part in hindering CBD. This means it is the fastest to feel results, but also the quickest to lose efficacy. CBD’s anti-inflammatory effects extend to being a bronchial dilator. This can mean an improvement in asthma or breathing related issues. It’s recommended to stick with topicals and oral applications if you are experiencing any lung issues you intend to treat with CBD. However, studies show it’s the smoke irritants that hold CBD back, making the CBD vaporizers a potential therapy for asthma, and other lung/breathing dysfunctions.

There are many other cannabinoids that are being explored at this time and research is constantly being updated as lengthy trials become published. At this time, there is confidence that CBD can help with the following:

• Analgesic​(pain relief)

• Anti-inflammatory​

• Antiemetic​ (anti-nausea)

• Anti-convulsive (anti-epilepsy)

• Anxiolytic and antidepressant​

• Appetite stimulant(certain cases)​

• Anti-angiogenic(prevent cancerous tumors from growing too big)​

• Anti-proliferative and anti-tumor(preventing the spread of cancer)​

• Palliative benefits​

• Antipsychotic (can reduce the psychotropic activity of THC)​

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Resources

1. Dosing research - https://pubmed.ncbi.nlm.nih.gov/29307505/

2. Insulin resistance - https://pubmed.ncbi.nlm.nih.gov/35628194/

3. Asthma - https://pubmed.ncbi.nlm.nih.gov/32286026/